Over a 169 fuel fills my 1991 ST1100 has an average fuel consumption of 43.30 MPG, best was 54.67 MPG. This is mixed riding 2 lane roads, interstates, solo and 2 up riding, loaded and unloaded.
Now with that said my wife rode a 2000 ST1100 and when we would travel together she would always get 5 mpg better than I. I have now started to ride her 2000 and it is about the same as my 1991. The biggest variable here is, I am 75 pounds heavier than my wife. I believe this is the biggest contributing factor for the 5 mpg difference. No pun intended.