My Sporty had >7,000 Kilometers (roughly 4,300 miles) on HD tires when I replaced them with Metzlers. I found them to be very hard and slippery for my style of riding. I tend to lean more and take corners faster than your average cruiser rider. This was in the spring when the weather was still in the 60's
I plain loved the Avons on my ST1100 they held good in rain, cold and hot weather. Second choice was Metzlers. The Metzlers are much better on the HD than what factory tires were. I now have put on 15,000 KMs or 9,000 miles on the Metzlers and they are now getting slippery in a pouring rain (man, I miss the tupperware); I may have to get a new set for the colder, sometimes morning frost, weather.
You may find that they will wear for many miles, but if you drive in all weather, specially cold and wet, I would take it easier in the turns; depends on what you are used to riding on and your riding style.
Hope this helps,
JD