After 5 trips between Cedar City and Elk Grove Kaliforniastan (10 miles south of Sacramento), I can tell you a couple of things.
1. Going up US50 from Sacramento, there is some construction just east of US99. It's about 10 miles worth...I think). If you hit it during rush hour, it will be a mess.
2. US50, before US89 (to go catch US88 east) there are several areas where they are taking out a bunch of burned out trees. You can be delayed anywhere from 15minutes to 1/2 hour, plus or minus a few minutes.
3. If you are going to Ely, NV, Via US50, there is not much gas between Fallon, NV and Ely, and it is about 260 miles. I'm not sure what your range is on a ST1100, but I had a little left over, when I was riding between them on my 2012 ST1300 (heading west in 27F weather.)
Good luck, it should be an enjoyable ride, if you don't push yourself too much!